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A sub-chronic toxicity study of mercuric chloride in the rat
Joint Authors
Naik, Rajashri Ramakrishan
Urayqat, Ghalib Ali
Salim, Tahiyah H.
Musa, Said Z.
al-Jundi, Reda M.
Source
Jordan Journal of Biological Sciences
Issue
Vol. 5, Issue 2 (30 Jun. 2012), pp.141-146, 6 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2012-06-30
Country of Publication
Jordan
No. of Pages
6
Main Subjects
Topics
Abstract EN
Heavy metal accumulates mostly in mammalian liver and kidney as these organs involved in the detoxification and excretion of foreign materials.
Chronic exposure of heavy metals leads to intoxication of these organs.
In the present study sub-chronic effect of mercury (as mercuric chloride at a dose of 3.75 mg / kg body weight) on biochemical parameter was studied on the experimental animals.
Results revealed that mercury increased the aspartate transpeptidase (AST), alanine transpeptidase (ALT), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) activities significantly than control group.
This study also indicates that mercury increases the level of urea and creatinine ; and decreases the iron level.
Bioaccumulation of mercury was higher in kidney as compared to other organs.
American Psychological Association (APA)
Urayqat, Ghalib Ali& Salim, Tahiyah H.& Naik, Rajashri Ramakrishan& Musa, Said Z.& al-Jundi, Reda M.. 2012. A sub-chronic toxicity study of mercuric chloride in the rat. Jordan Journal of Biological Sciences،Vol. 5, no. 2, pp.141-146.
https://search.emarefa.net/detail/BIM-311192
Modern Language Association (MLA)
Urayqat, Ghalib Ali…[et al.]. A sub-chronic toxicity study of mercuric chloride in the rat. Jordan Journal of Biological Sciences Vol. 5, no. 2 (Jun. 2012), pp.141-146.
https://search.emarefa.net/detail/BIM-311192
American Medical Association (AMA)
Urayqat, Ghalib Ali& Salim, Tahiyah H.& Naik, Rajashri Ramakrishan& Musa, Said Z.& al-Jundi, Reda M.. A sub-chronic toxicity study of mercuric chloride in the rat. Jordan Journal of Biological Sciences. 2012. Vol. 5, no. 2, pp.141-146.
https://search.emarefa.net/detail/BIM-311192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 145-146
Record ID
BIM-311192