Lack of association between ARMS2 polymorphism and age-related macular degeneration among Jordanians
Joint Authors
al-Khatib, Asim M.
Abu Arqub, Duaa A.
al-Khatib, Shadi Q.
Source
Jordan Journal of Biological Sciences
Issue
Vol. 5, Issue 4 (31 Dec. 2012), pp.261-264, 4 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2012-12-31
Country of Publication
Jordan
No. of Pages
4
Main Subjects
Topics
Abstract EN
Multiple, genetic factors have, recently been characterized as risk factors for age-related .macular deecnerafion (AMD).
ARMS2 gene polymorphism, rs 10490924, was associated with AMD.
This case-control analyzed the role of ARMS2 gene among Jordanians with AMD.
Forty two AMD patients and 84 controls were recruited and genotyped for rsl 0490924 of ARMS2 gene.
Genotypic distribution of the ARMS2 polymorphism was not different among AMD patients compared to controls (p = 0.20).
Allelic distribution was also insignificant among AMD patients (allele frequency 0.33) compared to control (allele frequency 0.23).
This study was the first that screen AMD ARMS2 gene polymorphism among Jordanians.
Further studies with larger sample size and different set of patients might be needed to confirm our conclusion.
American Psychological Association (APA)
al-Khatib, Asim M.& Abu Arqub, Duaa A.& al-Khatib, Shadi Q.. 2012. Lack of association between ARMS2 polymorphism and age-related macular degeneration among Jordanians. Jordan Journal of Biological Sciences،Vol. 5, no. 4, pp.261-264.
https://search.emarefa.net/detail/BIM-311203
Modern Language Association (MLA)
al-Khatib, Asim M.…[et al.]. Lack of association between ARMS2 polymorphism and age-related macular degeneration among Jordanians. Jordan Journal of Biological Sciences Vol. 5, no. 4 (Dec. 2012), pp.261-264.
https://search.emarefa.net/detail/BIM-311203
American Medical Association (AMA)
al-Khatib, Asim M.& Abu Arqub, Duaa A.& al-Khatib, Shadi Q.. Lack of association between ARMS2 polymorphism and age-related macular degeneration among Jordanians. Jordan Journal of Biological Sciences. 2012. Vol. 5, no. 4, pp.261-264.
https://search.emarefa.net/detail/BIM-311203
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 263-264
Record ID
BIM-311203