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The role of vaginal prolactin in diagnosis of premature rupture of membranes
Joint Authors
Kariman, N.
Hedayati, M.
Majd, S. H. Alavi
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 6 (30 Jun. 2012), pp.352-357, 6 p.
Publisher
Publication Date
2012-06-30
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Premature rupture of membranes (PROM) is one of the most common complications of pregnancy that has a major impact on pregnancy outcomes.
A diagnostic tool that is non-invasive, specific and quick is needed to predict PROM.
The purpose of this study was to evaluate the diagnostic power of the vaginal washing fluid prolactin for the diagnosis of premature rupture of membranes and to determine cut-off values.
Methods : A total of 114 pregnant women were recruited in this diagnostic trial.
The PROM group consisted of 54 pregnant women between 20 and 41 weeks of gestation with diagnosis of confirmed PROM [amniotic fluid pooling and Nitrazine paper test (+) and fernt test (+)].
The control group consisted of 60 pregnant women between and 41 weeks of gestation without any complaint or complication.
All patients underwent speculum examination for amniotic fluid pooling, nitrazine paper test, fern test, vaginal washing fluid prolactin sampling.
Results : Vaginal fluid concentrations of prolactin was significantly different between the two groups (P < 0.001).
The sensitivity, specificity, positive and negative predictive values and accuracy were 87.03 %, 75.0 %, 75.80 %, and 83.33 % in detecting PROM by evaluation of vaginal fluid prolactin concentration with a cut-off value of 9.50 Μiu / ml, respectively.
Conclusion : The prolactin levels in the washing fluid of the posterior vaginal fornix in our experience is reliable and non-invasive diagnostic tests of PROM.
American Psychological Association (APA)
Kariman, N.& Hedayati, M.& Majd, S. H. Alavi. 2012. The role of vaginal prolactin in diagnosis of premature rupture of membranes. Iranian Red Crescent Medical Journal،Vol. 14, no. 6, pp.352-357.
https://search.emarefa.net/detail/BIM-311688
Modern Language Association (MLA)
Kariman, N.…[et al.]. The role of vaginal prolactin in diagnosis of premature rupture of membranes. Iranian Red Crescent Medical Journal Vol. 14, no. 6 (Jun. 2012), pp.352-357.
https://search.emarefa.net/detail/BIM-311688
American Medical Association (AMA)
Kariman, N.& Hedayati, M.& Majd, S. H. Alavi. The role of vaginal prolactin in diagnosis of premature rupture of membranes. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 6, pp.352-357.
https://search.emarefa.net/detail/BIM-311688
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 356-357
Record ID
BIM-311688