The association between Y chromosome microdeletion and recurrent pregnancy loss
Joint Authors
Khorshid, H. R. Khorram
Kamali, K.
Ghorbian, S.
Saliminejad, K.
Sadeghi, M. R.
Javadi, Gh. R.
Amirjannati, N.
Bahreini, F.
Edalatkhah, H.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 6 (30 Jun. 2012), pp.358-362, 5 p.
Publisher
Publication Date
2012-06-30
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : To date, the role of male factor contributing in evaluation of spontaneous recurrent pregnancy loss (RPL) has been less investigated and there is discrepancy in the role of Y chromosome microdeltions in RPL.
Therefore, the current study was designed to examine whether Y chromosome microdeletions were associated with RPL in an Iranian population.
Methods : One hundred men from couples, experiencing three or more RPLs, and one hundred normal men from couples with at least one child and no history of miscarriages as control group were included.
Genomic DNA was extracted from peripheral blood and tested for Y chromosome microdeletions in AZFa, AZFb and AZFc regions using two multiplex PCR.
Results : None of the men in the case and control groups had any microdeletions in the AZFa, AZFb and AZFc Regions.
Conclusion : It seems that Y chromosome microdeletion is not associated with recurrent pregnancy loss, therefore performing this test in Iranian couples with RPL is not recommended.
American Psychological Association (APA)
Ghorbian, S.& Saliminejad, K.& Sadeghi, M. R.& Javadi, Gh. R.& Kamali, K.& Amirjannati, N.…[et al.]. 2012. The association between Y chromosome microdeletion and recurrent pregnancy loss. Iranian Red Crescent Medical Journal،Vol. 14, no. 6, pp.358-362.
https://search.emarefa.net/detail/BIM-311689
Modern Language Association (MLA)
Ghorbian, S.…[et al.]. The association between Y chromosome microdeletion and recurrent pregnancy loss. Iranian Red Crescent Medical Journal Vol. 14, no. 6 (Jun. 2012), pp.358-362.
https://search.emarefa.net/detail/BIM-311689
American Medical Association (AMA)
Ghorbian, S.& Saliminejad, K.& Sadeghi, M. R.& Javadi, Gh. R.& Kamali, K.& Amirjannati, N.…[et al.]. The association between Y chromosome microdeletion and recurrent pregnancy loss. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 6, pp.358-362.
https://search.emarefa.net/detail/BIM-311689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 362
Record ID
BIM-311689