Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus
Joint Authors
Yusuf, Dua Muhammad
Fawzi, Fatin Muhammad
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 23, Issue 5 (31 Oct. 2012), pp.985-992, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2012-10-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
Constant increase in the incidence of type-1 diabetes (T1-DM) has made it necessary to have new markers for the early detection of diabetic nephropathy (DN).
One of the markers that could be helpful in detecting functional alterations in renal hemodynamics is assessment of the renal resistive index (RI) by using renal Doppler.
We studied 25 patients with T1-DM (Group-A), which comprised of 15 females and 10 males, with a mean age of 10.8 ± 2.2 years and duration of diabetes of 5 ± 1.1 years.
A control group (Group-B) comprising 20 healthy 12 children.
females and eight males with mean age of 11.6 ± 2 years, was also studied.
The following parameters were studied in the two groups : age, serum creatinine, albumin excretion rate (AER), glomerular filtration rate (GFR), glycosylated hemoglobin (HbA1c) and mean renal RI of both kidneys.
We found an increase in the mean RI in diabetic patients versus healthy children ; the mean RI in Group-A was 0.64 ± 0.55 while it was 0.58 ± 0.0.28 in Group-B (P < 0.000).
This increase in RI had a positive correlation with duration of the disease, GFR and HbA1c levels, but there was no correlation with serum creatinine or AER.
We conclude that RI is increased early in TI-DM, and it can be a predictor of DN.
American Psychological Association (APA)
Yusuf, Dua Muhammad& Fawzi, Fatin Muhammad. 2012. Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 5, pp.985-992.
https://search.emarefa.net/detail/BIM-311767
Modern Language Association (MLA)
Yusuf, Dua Muhammad& Fawzi, Fatin Muhammad. Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 5 (Oct. 2012), pp.985-992.
https://search.emarefa.net/detail/BIM-311767
American Medical Association (AMA)
Yusuf, Dua Muhammad& Fawzi, Fatin Muhammad. Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 5, pp.985-992.
https://search.emarefa.net/detail/BIM-311767
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 991-992
Record ID
BIM-311767