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Orofacial clefts and risk factors in Tehran, Iran : a case control study
Joint Authors
Mushrif, M.
Taghavi, N.
Mollaian, M.
Alizadeh, P.
Modabernia, Sh.
Akbarzadeh, A. R.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 1 (31 Jan. 2012), pp.25-30, 6 p.
Publisher
Publication Date
2012-01-31
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Non-syndromic cleft lip with or without cleft palate (CL / P) or cleft palate only (CPO) are orofacial clefts with multifactorial etiology.
These include environmental factors and heterogeneous genetic background.
Therefore, studies on different and homogenous populations can be useful in detecting related factors.
The aim of the present study was to evaluate the risk factors in patients with non-syndromic cleft in Tehran, Iran.
Methods : Data from 300 patients and 300 controls were collected between 2005 and 2010.
Binary logistic regression analyses were used to calculate relative risk by odds ratio (OR) and %95 confidence interval.
Results : Low maternal age (OR = 1.06, 95 % CI, 1.011-1.113), low socioeconomic status (OR = 0.23, 95 % CI, (0.07-0.007) maternal systemic disease (OR = 0.364; 95 % CI, 0.152-0.873) and passive smoking (OR = 0.613, 95 % CI, 0.430-0.874) increased the risk for CL / P and CPO.
There was a significant difference in iron and folic acid use during pregnancy when the case and control groups were compared.
Conclusion : In assessing for orofacial cleft risk, we should consider lack of folic acid supplementation use, maternal age and systemic diseases and passive smoking as risk factors.
American Psychological Association (APA)
Taghavi, N.& Mollaian, M.& Alizadeh, P.& Mushrif, M.& Modabernia, Sh.& Akbarzadeh, A. R.. 2012. Orofacial clefts and risk factors in Tehran, Iran : a case control study. Iranian Red Crescent Medical Journal،Vol. 14, no. 1, pp.25-30.
https://search.emarefa.net/detail/BIM-311804
Modern Language Association (MLA)
Taghavi, N.…[et al.]. Orofacial clefts and risk factors in Tehran, Iran : a case control study. Iranian Red Crescent Medical Journal Vol. 14, no. 1 (Jan. 2012), pp.25-30.
https://search.emarefa.net/detail/BIM-311804
American Medical Association (AMA)
Taghavi, N.& Mollaian, M.& Alizadeh, P.& Mushrif, M.& Modabernia, Sh.& Akbarzadeh, A. R.. Orofacial clefts and risk factors in Tehran, Iran : a case control study. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 1, pp.25-30.
https://search.emarefa.net/detail/BIM-311804
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 29-30
Record ID
BIM-311804