Evaluation and applicability of predictive equations of the glomerular filtration rate in chronic kidney disease
Joint Authors
Rao, Ambarkar Madhusudhana
Raghul, Manian
Kannapiran, Manickavasagam
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 23, Issue 4 (31 Aug. 2012), pp.827-831, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2012-08-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Prediction equations of glomerular filtration rate (GFR) may facilitate early detection, evaluation and management of chronic kidney disease (CKD).
However, the reliability of these equations was not extensively studied in our CKD population.
Hence, the present study was aimed to determine the performance of modification of diet in renal disease (MDRD) and Cockcroft Gault formulas in predicting GFR in CKD patients and their relationship with the measured GFR.
A total of 104 subjects (71 male and 33 female, aged 26–68 years) with different stages of CKD were recruited for this study; we excluded 51 patients due to improper collection of 24-h urine.
The GFR was measured using 24-h creatinine clearance and predicted by the Cockcroft Gault, the 4-variable MDRD and the 6-variable MDRD equations.
Prediction equations correlated well with the measured GFR.
However, the predicted GFR using the 4-variable MDRD equation revealed a highly significant positive correlation with the GFR measured by creatinine clearance (r = 0.86, P < 0.001), followed by the 6-variable MDRD and Cockcroft-Gault equations with r = 0.85 and 0.77, P < 0.001, respectively.
In conclusion, the present study predicts that the 4- variable MDRD is the best available equation for predicting GFR in our CKD population.
American Psychological Association (APA)
Raghul, Manian& Kannapiran, Manickavasagam& Rao, Ambarkar Madhusudhana. 2012. Evaluation and applicability of predictive equations of the glomerular filtration rate in chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 4, pp.827-831.
https://search.emarefa.net/detail/BIM-312271
Modern Language Association (MLA)
Raghul, Manian…[et al.]. Evaluation and applicability of predictive equations of the glomerular filtration rate in chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 4 (Aug. 2012), pp.827-831.
https://search.emarefa.net/detail/BIM-312271
American Medical Association (AMA)
Raghul, Manian& Kannapiran, Manickavasagam& Rao, Ambarkar Madhusudhana. Evaluation and applicability of predictive equations of the glomerular filtration rate in chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 4, pp.827-831.
https://search.emarefa.net/detail/BIM-312271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 830-831
Record ID
BIM-312271