Pattern of glomerular diseases among adults in Rajshahi, the Northern Region of Bangladesh

Abstract EN

To obtain a recent and comprehensive insight into the pattern of glomerular diseases in the Bangladeshi population, we studied 95 adequate renal biopsies done during July 2008 to June 2009, by light and direct immunofluorescence microscopy in the Department of Pathology, Rajshahi Medical College, and Northern Region of Bangladesh.

Of these, 38 (40 %) were males and 57 (60 %) were females, with a male to female ratio of 1 : 1.5.

The most frequent clinical presentation was nephritic syndrome (67.37 %).

Primary glomerular disease accounted for 91.25 % of all glomerular disease and, of them, focal and segmental meningeal proliferative glomerulonephritis was the most common histological lesion in 29.47 %.

Diffuse meningeal proliferative glomerulonephritis (GN) was the second most common lesion (15.79 %), followed by focal segmental GN (11.58 %), minimal change disease (10.53 %), membranous GN (7.37 %), IgAnephropathy (6.85 %), chronic Sclerosing GN (2.11 %) and crescentic GN (2.11%).

Lupus nephritis was the most prevalent among secondary GN.