Genetic study of phenylthiocarbamide (PTC) taste perception among six human populations of Jammu and Kashmir (India)
Joint Authors
Farid, Mohd
Shah, Ahsana
Husayn, Ruqayah
Afzal, Muhammad
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 13, Issue 2 (31 Aug. 2012), pp.161-166, 6 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2012-08-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : the ability to taste phenylthiocarbamide (PTC), a bitter chemical has long been known to be a bimodal autosomal trait inherited in a simple Mendelian recessive pattern which is being widely used for both genetic and anthropological studies.
The frequency of taster and non-taster allele is found to vary in different populations.
The present paper deals with the distribution of PTC tasting ability as a marker to study the genetic structure among Muslim populations of Jammu ; as no detailed information is available.
Aim : to investigate the prevalence and gene frequencies of PTC taste sensitivity among male and females.
Subjects and methods : we have undertaken a survey of gene frequencies of PTC taste ability for six different endogamous groups including tribal population.
PTC serial dilution method was used to assess the PTC taster and non-taster phenotypes.
Hardy–Weinberg method was used to determine allele frequencies.
Results : Gujarat and Bakarwal population showed highest PTC threshold while Syed had the least.
The phenotypic frequency for PTC taste ability varies within six populations; Syed were observed with highest taster frequency while Gujjar and Bakarwal had lowest taster frequency.
The taster frequency of six different populations showed that the percentage of taster frequency was more frequent than that of the non-tasters.
Also, females (v2 = 4.563, df = 5, p = 0.471) had more PTC tasters than males (v2 = 5.254, df =5, p = 0.385), being statistically significant.
The allelic frequencies in Gujjar and Bakarwal for non-taster (t) males and females were 55.86 and 54.55, respectively.
In Syed population, t-allele frequencies for males and females were 45.75 and 37.79, respectively, while the other four populations showed intermediate t-allele frequencies.
The heterozygosis showed little variation among all of the six populations.
American Psychological Association (APA)
Farid, Mohd& Shah, Ahsana& Husayn, Ruqayah& Afzal, Muhammad. 2012. Genetic study of phenylthiocarbamide (PTC) taste perception among six human populations of Jammu and Kashmir (India). The Egyptian Journal of Medical Human Genetics،Vol. 13, no. 2, pp.161-166.
https://search.emarefa.net/detail/BIM-312970
Modern Language Association (MLA)
Farid, Mohd…[et al.]. Genetic study of phenylthiocarbamide (PTC) taste perception among six human populations of Jammu and Kashmir (India). The Egyptian Journal of Medical Human Genetics Vol. 13, no. 2 (2012), pp.161-166.
https://search.emarefa.net/detail/BIM-312970
American Medical Association (AMA)
Farid, Mohd& Shah, Ahsana& Husayn, Ruqayah& Afzal, Muhammad. Genetic study of phenylthiocarbamide (PTC) taste perception among six human populations of Jammu and Kashmir (India). The Egyptian Journal of Medical Human Genetics. 2012. Vol. 13, no. 2, pp.161-166.
https://search.emarefa.net/detail/BIM-312970
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 166
Record ID
BIM-312970