The effect of fatty acids on the physico-chemical properties of different low molecular weight chitosan
Dissertant
Sad al-Nur, Muhammad Mustafa Khayr al-Din
Thesis advisor
Comitee Members
al-Umari, Mahmud Ahmad
Abu al-Halawah, Rajab
Ghanim, Raid Ahmad
University
Al albayt University
Faculty
Faculty of Sciences
Department
Department of Chemistry
University Country
Jordan
Degree
Master
Degree Date
2009
English Abstract
The objective of this thesis, to prepare a natural surfactants to be used in pharmaceutical industry as a replacement for synthetic surfactants system.
It has ability to decrease the surface tension of water.
As we know that chitosan compounds are insoluble in water due to the existence of hydrogen bonds for the chitosan itself (intra-molecular hydrogen bonding )and hydrogen bonds between different molecular weight chitosan ( inter-molecular hydrogen bonding) between the chitosan molecules, which increases the hydrophobicity of chitosan molecules to water molecules.
But this phenomena (insolubility in water) can be overcome by preparing new derivatives of chitosan compounds (surfactants) from different low molecular weight chitosans (1300, 6000, 10000, 18000 and 30000) Daltons (Da).
which reacted with fatty acid (butyric anhydride), and the resulted compounds has a high solubility in different aqueous medium (acidic- neutral -basic), because the fatty acid assist in decreasing of hydrogen bonds and increasing the distance between chitosan molecules (leads to decrease the hydrophobicity and increase the hydrophilicity).
The new compounds of chitosan can be recognized throughout the observation.
When chitosan derivative dissolved in water in a test tube and shacked, the foam was observed.
The foam appeared like the foam of soap this is indication of surfactants formation.
Because the soap one of the known surfactant.
The new compounds (surfactants) were recognize its Physico-chemical and compared with the properties of native chitosan.
The instruments used FT- IR, Nuclear Magnetic Resonance(1H- NMR), Deouy- Tensiometer for measuring the surface tension of the solution and Malvern Zetasizer to measure the particle size for both chitosan and its derivatives.
Main Subjects
Topics
No. of Pages
58
Table of Contents
Table of contents.
Abstract.
Chapter One : introduction.
Chapter Two : the aims of this work.
Chapter Three : results and discussions.
Chapter four
American Psychological Association (APA)
Sad al-Nur, Muhammad Mustafa Khayr al-Din. (2009). The effect of fatty acids on the physico-chemical properties of different low molecular weight chitosan. (Master's theses Theses and Dissertations Master). Al albayt University, Jordan
https://search.emarefa.net/detail/BIM-314880
Modern Language Association (MLA)
Sad al-Nur, Muhammad Mustafa Khayr al-Din. The effect of fatty acids on the physico-chemical properties of different low molecular weight chitosan. (Master's theses Theses and Dissertations Master). Al albayt University. (2009).
https://search.emarefa.net/detail/BIM-314880
American Medical Association (AMA)
Sad al-Nur, Muhammad Mustafa Khayr al-Din. (2009). The effect of fatty acids on the physico-chemical properties of different low molecular weight chitosan. (Master's theses Theses and Dissertations Master). Al albayt University, Jordan
https://search.emarefa.net/detail/BIM-314880
Language
English
Data Type
Arab Theses
Record ID
BIM-314880
