The relation of salivary antioxidants and lipid peroxidation biomarker to periodontal diseases among overweight and obese adult aged 55-65 year-old at textile factory in Mosul city

Abstract EN

Background: Overweight and obesity might be a potential risk factor for periodontal diseases.

The principle objective of this study was to identify the relationship of salivary antioxidants (vitamin E and uric acid) and lipid peroxidation biomarker (malondialdehyde / MDA) with periodontal diseases among overweight and obese adult aged 55-65 yearold subject at Textile factory in Mosul city. Materials and methods : All subjects aged 55-65 year-old (thirty five subjects) at Textile factory in Mosul city took part in this study.

Salivary flow rate was measured after collection of unstimulated saliva then salivary samples were analyzed for the measurement of salivary antioxidants (vitamin E and uric acid) and lipid peroxidation biomarker (malondialdehyde / MDA).

Periodontal diseases were evaluated by using the gingival index (GI), periodontal pocket depth (PPD) and clinical attachment level (CAL).

Body weight was determined by using the Body Mass Index (BMI). Results : Malondialdehyde (MDA) level was higher among obese and overweight than non-obese with highly significant difference (F = 5.52, P < 0.01).

Similarly vitamin E and uric acid levels were elevated among obese and overweight compared with non-obese though statistical differences were not significant (P > 0.05).

In contrast salivary flow rate was lower among obese and overweight than non-obese with highly significant difference (F = 8.11, P < 0.01). Regarding periodontal diseases, obese subjects showed higher periodontal destruction in comparison with nonobese. Conclusions : Overweight and obese subjects could be considered as special group who need educational and preventive programs that include maintaining a normal body weight, eating a well-balanced diet and engaging in physical activity in addition to oral hygiene practices to improve their oral and general health.