Biochemical analysis and periodontal health status in type 1 and type 2 diabetes : comparative study

Abstract EN

Background : diabetes mellitus is a group of metabolic disorders with one common manifestation : hyperglycemia.

This study aimed to evaluate the periodontal health status and cera reactive protein (C.R.P) in saliva in type1 and type 2 diabetic patients and compared with healthy subjects.

Material and method : total samples composed of eighty participants, the samples were divided to study group (60 diabetic patients) which include type 1 and type 2 diabetic patients and control group (20 healthy subjects).They were non-smokers male patients of age range 25-55 years old.

Periodontal health status was estimated by measuring plaque index (PL.I), Gingival index (G.I), Bleeding on probing (BOP), Probing pocket depth (PPD) and Clinical attachment level CAL).Five mls of UN stimulated whole saliva was collected for estimation of C.R.P.

Result : the result showed that the mean C.R.P in saliva was higher in study group compared to control group.

No significant difference in PL.I and significant difference in G.I, BOP, PPD and CAL between type 1 and type 2 of diabetes.

There was weak correlation between clinical periodontal parameters and biochemical parameters.

Conclusion : salivary C.R.P may be involved in the interaction of periodontitis in type 1 and type 2 diabetic patients.