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Effect of metformin therapy on reducing leptin resistance and enhancing ovulation in women with polycystic ovary syndrome
Author
Source
al-Kindy College Medical Journal
Issue
Vol. 8, Issue 2 (31 Dec. 2012), pp.65-68, 4 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2012-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Background : The relation between insulin resistance, leptin levels and other hormones in women with polycystic ovary syndrome(PCOS) is still controversial.
Metformin therapy is proved effective in reducing insulin resistance and also in some studies it was seen to be effective in reducing leptin levels.
Al-Kindy Col Med J 2012 ; Vol .8 No.
(2) p : 65 Objective : to study the effect of metformin on reducing leptin levels and enhancing ovulation in PCOS women.
Methods : metformin 500mg 3 times daily for 3 months was was given to 36 women with proved PCOS, in addition to that, other parameters were included.
Results : 28 women out of 36(77.78 %) showed an evidence of ovulation ovulation after 3 months of metformin therapy (p < 0.01) with significant ◌ٌ reduction in leptin levels (p < 0.001).
Conclusion : it can be concluded that metformin can reduce leptin resistance and enhance ovulation in PCOS women.
American Psychological Association (APA)
Tumah, Wafa Isa. 2012. Effect of metformin therapy on reducing leptin resistance and enhancing ovulation in women with polycystic ovary syndrome. al-Kindy College Medical Journal،Vol. 8, no. 2, pp.65-68.
https://search.emarefa.net/detail/BIM-316866
Modern Language Association (MLA)
Tumah, Wafa Isa. Effect of metformin therapy on reducing leptin resistance and enhancing ovulation in women with polycystic ovary syndrome. al-Kindy College Medical Journal Vol. 8, no. 2 (2012), pp.65-68.
https://search.emarefa.net/detail/BIM-316866
American Medical Association (AMA)
Tumah, Wafa Isa. Effect of metformin therapy on reducing leptin resistance and enhancing ovulation in women with polycystic ovary syndrome. al-Kindy College Medical Journal. 2012. Vol. 8, no. 2, pp.65-68.
https://search.emarefa.net/detail/BIM-316866
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 68
Record ID
BIM-316866