Antagonstic effect of lactobacillus fermentum supernatant against enterococcus faeciumand enterococcus faecalis in vitro

Abstract EN

Background : Lactobacillus fermentum selected as an alternative treatment to prevent or treat urogenital infection based on their probiotics properties and production of bacteriocins.

Objective : The present work was done to study the inhibition activity of L.

fermentum cell free supernatant against urogenital pathogens Enterococcus faecium and Enterococcus faecalisinvitro.

Materials and methods : L.fermentum isolates have been collected from vaginal swabs.

A supernatant of these isolates has been prepared and its antibacterial activity against 3 isolates of E.faecium and 3 isolates of E.faecalis has been studied.

Results : Different concentrations have been prepared and the most effective one was 1000μg / ml and the most affected isolate of E.faecalis was no.

3 which its MIC was 64μg / ml and MBC was 128 μg / ml, while the most affected isolate of E.

faecium was no.

1 which its MIC was 128 μg / ml and MBC was 256 μg / ml .

Conclusion : L.fermentum CFS showed significant activity against both Enterococcus isolates and showed closely related results.