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Local and systemic immune responses in rats infected with giardia iamblia
Joint Authors
Shani, Wafa Sadun
Abd al-Zahrah, Intiha
al-Malak, Maha Khalil
Source
The Medical Journal of Basrah University
Issue
Vol. 30, Issue 1 (30 Jun. 2012), pp.60-73, 14 p.
Publisher
University of Basrah College of Medicine
Publication Date
2012-06-30
Country of Publication
Iraq
No. of Pages
14
Main Subjects
Abstract EN
Objectives : This study was performed to determine the local (tissue) and systemic immune responses in rats infected with Giardia lamblia.
Materials and methods : Rattus noruigicus rats aged 2 months were inoculated with 103 Giardia lablia cyst.
After 7 and 14 days of infection samples (blood and small intestine) collected from both control and infected rats.
Local immune response was assessed by counting the inflammatory cells in small intestine, mast cell number and lymph node diameter.
Whearas systemic immune response was carried out by measurement of total and differential WBC count, phagocytic activity of polymphonuclear cells by NBT stain and histamine levels in blood plasma by ELISA kit.
Results: Results showed an infiltration of inflammatory cells in all parts of small intestine and an increasing in lymph nodules diameter.
Also, there is an infiltration of mast cells.
Results of systemic immune response revealed a high significant differences in total and differential WBC count between two studied groups.
Moreover, there was an increasing in phogocytic activity of polymorphonuclear cells and histamine plasma levels.
Conclusion : Recent data indicated that there is a local and systemic immune response during acute phase of Giardia lamblia infection in experimental animals.
American Psychological Association (APA)
Abd al-Zahrah, Intiha& Shani, Wafa Sadun& al-Malak, Maha Khalil. 2012. Local and systemic immune responses in rats infected with giardia iamblia. The Medical Journal of Basrah University،Vol. 30, no. 1, pp.60-73.
https://search.emarefa.net/detail/BIM-317146
Modern Language Association (MLA)
Abd al-Zahrah, Intiha…[et al.]. Local and systemic immune responses in rats infected with giardia iamblia. The Medical Journal of Basrah University Vol. 30, no. 1 (2012), pp.60-73.
https://search.emarefa.net/detail/BIM-317146
American Medical Association (AMA)
Abd al-Zahrah, Intiha& Shani, Wafa Sadun& al-Malak, Maha Khalil. Local and systemic immune responses in rats infected with giardia iamblia. The Medical Journal of Basrah University. 2012. Vol. 30, no. 1, pp.60-73.
https://search.emarefa.net/detail/BIM-317146
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 72-73
Record ID
BIM-317146