Molecular detection of some virulence gene associated with pathogenicity of klebsiella pneumoniae

Abstract EN

In this study, only seven isolates of Klebsiella pneumoniae were subjected for detection espB, cesT / eae, and CNF1 genes in their genome.It was seen that esp gene was not found in all isolates understudy, whereas cytotoxic necrotizing factor-1 (cnf1) was detected in four isolates of Klebsiella pneumoniae.

Moreover, three isolates were shown to possess cesT / eae gene in their genome.

The presence of such genes will provide the bacteria to invade and evade the host immune system and also will interfere with wound healing as a result of cnf1 production.