Study of some reproductive and hormonal risk factors in patients with breast cancer

Abstract EN

Breast cancer is the commonest malignancy in females and it has become a major health problem affecting women, worldwide.

Cancer cells are abnormal cells, grow and divide more quickly than healthy cells.

Some cancer cells form growths called tumors.

All tumors increase in size, but some tumors grow quickly, others slowly.

Cancer cells can spread to other parts of the body through the blood and lymph systems, this is called metastasis.

The aim of the study is to find the percentage of multiparous patients and the so the effect of parity state on the incidence of breast cancer, then their ages at first pregnancy and number of their children This study lasted from November / 2010 to May / 2011.There was 100 patients.

These patients were ranged from 26 to 75 years.

Full detailed information were taken from the patients in regarding the state of parity ,age of patient at first pregnancy and the number of children.

Seventy five percent of our one hundred patients were multiparous and twenty five percent were nulliparous, age of patients at first pregnancy were as 34.7 % at age ≤ 20 year, 37.3 % at the age group 21-25 years, 16 % at the age group 26-30 years, 5.3 % at age group 31-35 years and 6.7 % at age group 36-40 years, Those parous patients show 20% of them had 1-2 children, 44 % had 3-4 children, 17.3 % had 5-6 children, 13.3 % had 7-8 children and 5.3 % had > 8 children.

Breast cancer is a multifactorial disease with different parameters affecting its occurrence and then metastasis ,75 % of patients were multiparous and high percentage of them were less than thirty years indicating poor outcome ,while in regarding to the number of children in parous women, high percentage of patients were having higher parity rate.