Simultaneous spectrophotometric determination of tramadol and acetaminophen in pharmaceutical formulations using h-point standard addition method
Other Title(s)
التحديد الطيفي المتزامن للتركيبة الدوائية ل Tramadol و Acetaminophen باستخدام طريقة الإضافة القياسية للنقطة H
Joint Authors
Zirai, Ali Rida
Mardi, Kubra
Chalavi, Suhaylah
Source
Jordan Journal of Pharmaceutical Sciences
Issue
Vol. 6, Issue 1 (31 Jan. 2013), pp.48-55, 8 p.
Publisher
University of Jordan Deanship of Academic Research (DAR)
Publication Date
2013-01-31
Country of Publication
Jordan
No. of Pages
8
Main Subjects
Pharmacy, Health & Medical Sciences
Topics
Abstract AR
تم تطبيق طريقة الإضافة القياسية للنقطة H على أنه التحديد الطيفي المتزامن على المستحضرات الدوائية الآتية : Acetaminophen و Tramadol.
و أظهرت النتائج بأنه يمكن تحديدهم بتزامن 100-5.0 مل، على التوالي، و تم الحصول على حدود الكشف و هي 0.5-2.0 لـ.
Acetaminophen و Tramadol على التوالي.
كما أنه تم حساب معدل الانحراف المعياري للتحديد المتزامن المكرر 5 مرات.
و تم تطبيق الطريقة المقترحة بنجاح في كلا التركيبتين الدوائيتين.
Abstract EN
H-point standard addition method (HPSAM) was applied to the simultaneous spectrophotometric determination of tramadol and acetaminophen in pharmaceutical formulations.
The results showed that tramadol and acetaminophen can be determined simultaneously in the range 5.0-100 and 1.0-10 μg / ml, respectively.
The limits of detection (LOD) for tramadol and acetaminophen were obtained 2.0 and 0.50 μg / ml, respectively.
Relative standard deviation for five replicate simultaneous determinations of tramadol and acetaminophen were calculated to be 3.2 and 3.3 %, respectively.
The proposed method has been successfully applied to the simultaneous determination of tramadol and acetaminophen in some synthetic, pharmaceutical formulation.
American Psychological Association (APA)
Zirai, Ali Rida& Mardi, Kubra& Chalavi, Suhaylah. 2013. Simultaneous spectrophotometric determination of tramadol and acetaminophen in pharmaceutical formulations using h-point standard addition method. Jordan Journal of Pharmaceutical Sciences،Vol. 6, no. 1, pp.48-55.
https://search.emarefa.net/detail/BIM-319966
Modern Language Association (MLA)
Zirai, Ali Rida…[et al.]. Simultaneous spectrophotometric determination of tramadol and acetaminophen in pharmaceutical formulations using h-point standard addition method. Jordan Journal of Pharmaceutical Sciences Vol. 6, no. 1 (2013), pp.48-55.
https://search.emarefa.net/detail/BIM-319966
American Medical Association (AMA)
Zirai, Ali Rida& Mardi, Kubra& Chalavi, Suhaylah. Simultaneous spectrophotometric determination of tramadol and acetaminophen in pharmaceutical formulations using h-point standard addition method. Jordan Journal of Pharmaceutical Sciences. 2013. Vol. 6, no. 1, pp.48-55.
https://search.emarefa.net/detail/BIM-319966
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 53-54
Record ID
BIM-319966
