Studies on lungs and kidneys pathology in stillbirth mice from infected mothers with Schistosoma haematobium

Abstract EN

In the present work, 50 pregnant female Balb / c mice (20 control and, 30 infected by Schistosoma haematobium ).are included in the experiment .

exposure to cercaria occurs on 10th day of pregnancy (midperiod of pregnancy) with continuous low concentration of cercaria for 5 days. Abortions occur after 7-8days after first exposure (17th-18th day of pregnancy) .

Histopahtological studies of the stillbirths revealed very marked changes including Lymphocytic infiltrations within the parenchyma of the alveoli, Congestion, haemorrhage and necrosis in the lung.

The main pathological changes in kidney were atrophic glomeruli, rupture of parietal layer of Bowman’s capsule, necrosis and tubular atrophy.