Evaluation of lipid and lipoprotein profile in patients with type 2 diabetes
Joint Authors
Ajlan, Salman Kazim
Mahmud, Maryam S.
al-Nimah, Lamya M.
Source
The Medical Journal of Basrah University
Issue
Vol. 28, Issue 1 (30 Jun. 2010), pp.27-32, 6 p.
Publisher
University of Basrah College of Medicine
Publication Date
2010-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
Objective : to evaluate the pattern of lipid and lipoprotein profile in patients with type 2 diabetes (T2D).
Methods : in this prospective study, which was carried out in Basrah, Southern Iraq, serum concentrations of glucose fasting blood sugar” (FBS), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), triglycerides (TG) and very low density lipoprotein-cholesterol (VLDL-C) were measured in 92 patients (43 males and 49 females) with T2D and 120 control subjects (35 males and 85 females).
Results : pPatients with T2D have significantly higher serum concentrations of TC, LDL-C, TG, VLDL-C and LDLC/HDL-C ratio (P<0.001) and significantly lower HDL-C serum concentration (P < 0.001) compared to control subjects.
Male patients with T2D showed significantly higher TC, LDL-C serum concentrations and LDL-C / HDL-C ratio in comparison to control subjects (P < 0.001), while serum HDL-C concentration was significantly lower among T2D patients compared to controls (P < 0.001).
No significant differences were seen in serum TG and VLDL-C concentrations between male patients and control subjects (P>0.05).
In females, serum levels of TC, LDL-C, TG, VLDL-C, and LDL-C / HDL-C ratio were significantly higher (P < 0.001), and serum HDL-C level was significantly lower (P < 0.05) in patients with T2D than in control subjects.
Conclusion : T2D has marked effects on lipid and lipoprotein profile causing a diversity of dyslipidaemia, that might lead to atherosclerosis, and hence, increasing the risk of coronary heart disease.
American Psychological Association (APA)
al-Nimah, Lamya M.& Ajlan, Salman Kazim& Mahmud, Maryam S.. 2010. Evaluation of lipid and lipoprotein profile in patients with type 2 diabetes. The Medical Journal of Basrah University،Vol. 28, no. 1, pp.27-32.
https://search.emarefa.net/detail/BIM-320849
Modern Language Association (MLA)
al-Nimah, Lamya M.…[et al.]. Evaluation of lipid and lipoprotein profile in patients with type 2 diabetes. The Medical Journal of Basrah University Vol. 28, no. 1 (2010), pp.27-32.
https://search.emarefa.net/detail/BIM-320849
American Medical Association (AMA)
al-Nimah, Lamya M.& Ajlan, Salman Kazim& Mahmud, Maryam S.. Evaluation of lipid and lipoprotein profile in patients with type 2 diabetes. The Medical Journal of Basrah University. 2010. Vol. 28, no. 1, pp.27-32.
https://search.emarefa.net/detail/BIM-320849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 30-32
Record ID
BIM-320849