Pathological study on the effect of probiotic in chickens infected with E. Coli

Abstract EN

The present study was conducted to evaluate the efficacy of ROEMIN W2 (a combination of Lactobacillus acidophilus, Lactobacillus thermophilus, Bifidobacterium and lactose) on prevention and / or treatment of broiler chicks infected with E.Coli.

One hundred fifty-one day old chicks were divided into five equal groups, (GpI) served as control none treated none infected.

(Gp II) received probiotic only, (Gp III) infected only with E.Coli, (Gp IV) received probiotic then infected with E.

coli and kept as protective group and (GP V) infected firstly with E.Coli then treated with probiotic.

At the end of every week till six week blood samples were collected for biochemical studies.

Specimens from liver, intestine, heart, kidney and lymphoid organs were collected for histopathological studies.

Results revealed significant increase of body weight, weight gain and FCR in group II compared with other groups.

Histopathological results revealed obvious improvement in intestinal histomorphology, no changes in the liver, kidney, lung and hyperplasia of lymphoid follicles of payer’s patches and lymphoid organs in gpII.

Severe destruction, atrophy and degeneration of all organs with severe perihepatitis, pericarditis and lymphoid depletion in gp III were observed.

Mild changes were observed in gpIV.

Moderate to severe changes were observed in gpV.