Antileishmanial activity of alcoholic extract of (Trigonella foenum-graecum) seeds against ulceration of cutaneous leishmaniasis in vivo
Joint Authors
Jar Allah, Hind Mahdi
Mahdi, Dawud Salman
Source
al-Kufa University Journal for Biology
Issue
Vol. 3, Issue 2 (31 Dec. 2011)6 p.
Publisher
University of Kufa Faculty of Science Department of live Sciences
Publication Date
2011-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract AR
تم دراسة تأثير المستخلص الكحولي لبذور نبات الحلبة على الآفات المتقرحة لداء الشمانيا الجلدي المتسبب عن سلالة Leishmania major في الفئران المختبرية نوع BALB / c المحقونة تجريبيا بالطور المسوط للطفيلي.
تم عزل سلالة Leishmania major من مريض عراقي مصاب بداء اللشمانيا الجلدي، المريض يعيش في قرية ريفية تعود إلى أهوار البصرة.
تم إعطاء المستخلص الكحولي لهذا النبات عن طريق الحقن داخل الآفة.
أظهر المستخلص الكحولي لبذور نبات الحلبة نتائج جيدة حيث قلل من تطور و نمو القرح الجلدية و أحجامها للفئران المعالجة عندما تم مقارنتها مع فئران السيطرة التي كانت ذا زيادة في أحجام القرح و أكثر سوءا.
Abstract EN
The effect of alcoholic extract from Trigonella foenum-graecum seeds was studied on the ulcerative lesions of cutaenous leishmaniasis caused by Leishmania major in BALB/c mice experimentally infected with L.
major promastigotes.The Leishmania major strain was isolated from Iraqi patient suffered from cutaneous leishmaniasis, the patient lives in rural village belong to Basrah marshland.
The alcoholic extract of this plant was administrated by intralesion injection.The alcoholic extract from Trigonella foenum-graecum seeds showed good results.
The plant extract decrease the growth and development the cutaneous ulcers and its size of treated mice when compared to the control mice which were worsening and more increased in ulcers size.
American Psychological Association (APA)
Jar Allah, Hind Mahdi& Mahdi, Dawud Salman. 2011. Antileishmanial activity of alcoholic extract of (Trigonella foenum-graecum) seeds against ulceration of cutaneous leishmaniasis in vivo. al-Kufa University Journal for Biology،Vol. 3, no. 2.
https://search.emarefa.net/detail/BIM-322021
Modern Language Association (MLA)
Jar Allah, Hind Mahdi& Mahdi, Dawud Salman. Antileishmanial activity of alcoholic extract of (Trigonella foenum-graecum) seeds against ulceration of cutaneous leishmaniasis in vivo. al-Kufa University Journal for Biology Vol. 3, no. 2 (2011).
https://search.emarefa.net/detail/BIM-322021
American Medical Association (AMA)
Jar Allah, Hind Mahdi& Mahdi, Dawud Salman. Antileishmanial activity of alcoholic extract of (Trigonella foenum-graecum) seeds against ulceration of cutaneous leishmaniasis in vivo. al-Kufa University Journal for Biology. 2011. Vol. 3, no. 2.
https://search.emarefa.net/detail/BIM-322021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-322021