Liver function tests in toxoplasmosis

Abstract EN

Objective : To highlight the possible effects of toxoplasmosis on serum activities of liver enzymes.

Methods : Sixty serologically toxoplasmosis positive women referred to the Public Health Laboratory Centre in Nineveh Province were enrolled during the period from Oct.

2008–March 2009.

Their ages ranged between 16-35 years and mean ±SD (24.9 ± 4.8 years).

Cases were compared with 40 age matched apparently healthy high school, medical college students and employees of Mosul College of Medicine control women who were serologically negative for toxoplasmosis ; their ages ranged between 17-35 years and mean ± SD (23.9 ± 5.5years).

Serum activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and lactate dehydrogenase (LDH) were measured in all cases and controls.

Results : Liver enzymes activities were higher in patients compared with those of the controls.

Conclusion : A probable involvement of the liver in the disease process was noticed for the toxoplasmosis patients although not sufficient to produce clinical signs and symptoms of liver disease.