Some studies on clostridium colinum infection in chickens and qoails

Abstract EN

Forty samples (liver, spleen, and intestine) from freshly dead quails and ninety five samples (liver, spleen and intestine) from freshly dead chickens (1–18 month age) were collected from different farms of Assiut governorate.

Cl.colinum was isolated from quails and chickens at a rate of 70 % and 27.4 % respectively.

Experimental infection of 5–week old quails intramuscular with isolated Cl.colinum form chickens revealed 100 % mortality within 2-4 days post inoculation while 100 % mortality within 8 days post inoculation was reported in orally infected quails.

Intramuscular experimental infection of 12–day old chickens with isolated Cl.

cilium caused 70 % mortality within 48h.

Post inoculation.

Resolution of Cl.

cilium from inoculated quails and chickens was successful.

Histopathologically study revealed the intestine and liver were the most organs affected in chickens and quail infected.

The intestine revealed epithelial necrosis desquamation, ulcerations and inflammatory cell infiltrations.

The liver showed fatty degeneration, hepatocyte necrosis with moderate inflammatory cell infiltrations.

Changes in glandular stomach were additionally reported in some infected chickens and myocardial necrosis was observed in one infected chicken.

In vitro sensitivity test showed that gentamycin, ampicillin and naladixic acid were the most effective drugs.