Some studies on bacteria induction of renal lesions in chikens

Abstract EN

Eighty samples from enlarged congested kidneys were collected from freshly dead chickens form different farms of Assiut Governorate (and didn't suffer from any ration problem).

These samples were taken to isolate some bacteria which affect kidneys.

After biochemical reactions, the isolation revealed presence of 8 organisms: E.coli at a rate of (70 %)– Staph.

aurous ( 37.5 % )-Corynebacterium ( 31.3 % )–Klebsiella ( 15 % ) – Proteus ( 18.8 % )–Pseudomonas ( 11.3 % )– Clostridium perfringenes ( 8.8 % )– Enterococcus facials ( 6.3 % ).

Experimental infection of 11 day–old chicken subcutaneously with isolated E.coli and Corynebacterium showed mortality rates of 60 % 20 % respectively within 7 days postinoculation.

Before death birds were depressed, huddling together and couldn't move.

Postmortem examination revealed congestion and enlargement of kidneys, liver and spleen and the ureters were filled with uprate.

Birds which inoculated orally didn't show any clinical signs.

21 days post inoculation all birds were sacrificed, P.M examination revealed congestion and enlargement of kidneys ant the ureters were distended with ureter.

Some birds formed stones in the ureters.

Resolution of the 2 organisms from kidneys of experimentally infected birds was successful.

Histopathologically study revealed that interstitial nephritis in the forms of blood vessel congestion and hemorrhage tubular cell degeneration mononuclear cell infiltration and glomerular hypercellutarity are the most permanent lesions in bacterial infected chicken.

In vitro sensitivity test revealed that neomycin, gentamycin and Trimethoprim are the most effective drugs for E.coli while erythromycin, rifampin and gentamycin are the most effect for Corynebacterium.