Seasonal measurement of serum total cholesterol and malondialdehyde in healthy subjects

Abstract EN

Objective : To evaluate serum total cholesterol (TC) and malondialdehyde (MDA) in healthy subjects in winter and summer seasons.

Subjects and methods : This study was conducted at the college of Pharmacy, University of Mosul.

Twenty healthy subjects, non-smokers, free from any medication were included in this study.

Five mL of blood sample from each subject was taken in winter and other blood sample was taken from the same subject in summer and analysed for serum TC and MDA.

Results : No significant difference was noticed between winter and summer for serum TC (4.65 ± 0.59 mmol / L versus 4.45 ± 0.6 mmol / L).

However, serum MDA in summer (1.19 ± 0.2 μmole / L) was significantly higher (P < 0.01) than in winter (0.96 ± 0.16 μmol / L) Conclusion : Oxidative stress increases in hot weather.

Seasonal serum lipid profile levels depend on life style of the people and their geographical location.