Histopathological evaluation of aragonitic calcium carbonate as a bone graft substitute in rabbit's mandible : an experimental study
Joint Authors
al-Sudani, Kazim A.
Ibrahim, Samir W.
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 24, Issue 4 (31 Dec. 2012), pp.58-61, 4 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2012-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background : Augmentation of the craniomaxillofacial region is required for many aesthetic and reconstructive procedures.
Many bone grafts substitutes have been developed .These products differ in their osteoconductive and osteoinductive properties .The use of bone graft substitutes offers the ability to lessen the possible morbidity of the harvest site inautograft.
Aragonitic calcium carbonate has proved to have biocompatible properties as bone graft substitute.
This study aimed to evaluate the histopathological effects of aragonitic calcium carbonate in experimentally induced bone defect in rabbit's mandible. Material and method : Twenty five adult male healthy rabbits were used in current study.
Two holes were prepared in the rabbit's mandible, first hole remain empty as control, the second filled with aragonitic calcium carbonate. Samples were taken after 2, 6, 8, 12 and 24 weeks.
Histopathological evaluation include; examination of new bone formation and inflammatory response, in both control and experimental groups. Results : At 2 weeks, there was no new bone formation in both defects with moderate amount of inflammation.
At 6, 12 and 24 weeks the amount of new bone formation in implant group was more than that formed in control group (statistically highly significant correlation, p < 0.01).
At 8 weeks, less bone amount in implant group .There were marked degradation of implant particles at 6 weeks. Conclusions : ACC is suitable bone graft substitute and induce new bone formation by acting as bioactive, osteoconductive bone graft when come in contact with bone.
American Psychological Association (APA)
Ibrahim, Samir W.& al-Sudani, Kazim A.. 2012. Histopathological evaluation of aragonitic calcium carbonate as a bone graft substitute in rabbit's mandible : an experimental study. Journal of Baghdad College of Dentistry،Vol. 24, no. 4, pp.58-61.
https://search.emarefa.net/detail/BIM-324159
Modern Language Association (MLA)
Ibrahim, Samir W.& al-Sudani, Kazim A.. Histopathological evaluation of aragonitic calcium carbonate as a bone graft substitute in rabbit's mandible : an experimental study. Journal of Baghdad College of Dentistry Vol. 24, no. 4 (2012), pp.58-61.
https://search.emarefa.net/detail/BIM-324159
American Medical Association (AMA)
Ibrahim, Samir W.& al-Sudani, Kazim A.. Histopathological evaluation of aragonitic calcium carbonate as a bone graft substitute in rabbit's mandible : an experimental study. Journal of Baghdad College of Dentistry. 2012. Vol. 24, no. 4, pp.58-61.
https://search.emarefa.net/detail/BIM-324159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 61
Record ID
BIM-324159