Effect of pyocyanine extracted from P. aeroginosa on other pathogenic bacteria in vitro

Abstract EN

Clinical isolates of Pseudomonas aeroginosa was tested for their inhibitory effect on growth of other pathogenic bacteria, Pyocyanine (PCN) is the major metabolites of this bacteria, the pigmented strain were found to have stronger antimicrobial activity on Gram's +ve and Gram's–ve bacteria than unpigmented one.

Our results revealed the PCN have strongly active against Staph.

aureus & E.coli ,but weakly effect of Klebs.

& Proteus, other strains of P.aeroginosa are not affected by PCN.