Pathological study on some tissues of rat experimentally infected with Toxoplasma gondii

Abstract EN

This study was conducted to isolate Toxoplasma gondii from aborted placentae of ewes, and follow up the histopathological changes that produced in some different organs such as liver, brain and eyes of rats which inoculated experimentally by suspension of the parasite.

Histopathological changes in brain represented by presence of tachyzoites and tissue cyst at 30 / 45 days post infection associated with encephalomeningitis–while in liver, the lesions characterized by presence of perivascular and periductular cuffing of tachyzoites associated with pyknotic nuclei of hepatocytes.

Moreover, in the eye tachyzoites and tissue cyst has been seen invaded in extraocular muscles, congestion of blood vessels with lymphocytic infiltration and retinochoroiditis, also has been seen.