Modification of the mechanical properties of red blood cell membrane by spent plasmodium falciparum culture supernatant
Joint Authors
Source
Jordan Journal of Biological Sciences
Issue
Vol. 6, Issue 1 (31 Mar. 2013), pp.25-29, 5 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2013-03-31
Country of Publication
Jordan
No. of Pages
5
Main Subjects
Topics
Abstract EN
The effect of spent culture supernatant on RBC membrane mechanical properties, RBC membrane deformability and stability, were assayed by ektacytometry after treating RBC ghost membranes with spent Plasmodium falciparum (P.falciparum) malaria culture supernatant fluid (Pf(+)), malaria culture medium which had not been exposed to P.
falciparum infected RBCs Pf (-), and malaria culture medium from an in vitro culture system containing uninfected RBCs (M).
All treated RBC membranes were less deformable, and more stable than control, untreated RBC membranes.
However, compared to controls, Pf(+)-treated RBC membranes were more deformable than both Pf (-)-treated and M-treated RBC membranes.
Similarly, Pf (+)-treated RBC membranes were more stable than membranes treated with both Pf (-) and M.
The deformability and stability of Pf (+)-treated RBC membranes were significantly different from membranes treated with both Pf (-) and M (P ≤ 0.05).
However, there was no significant difference between deformability and membrane stability for Pf (-) treated and M-treated RBC membranes.
Our results suggest that spent P.
falciparum culture supernatant may significantly modify RBC membrane mechanical properties.
American Psychological Association (APA)
Aryee, Nii A.& Takakuwa, Yuichi. 2013. Modification of the mechanical properties of red blood cell membrane by spent plasmodium falciparum culture supernatant. Jordan Journal of Biological Sciences،Vol. 6, no. 1, pp.25-29.
https://search.emarefa.net/detail/BIM-326514
Modern Language Association (MLA)
Aryee, Nii A.& Takakuwa, Yuichi. Modification of the mechanical properties of red blood cell membrane by spent plasmodium falciparum culture supernatant. Jordan Journal of Biological Sciences Vol. 6, no. 1 (Mar. 2013), pp.25-29.
https://search.emarefa.net/detail/BIM-326514
American Medical Association (AMA)
Aryee, Nii A.& Takakuwa, Yuichi. Modification of the mechanical properties of red blood cell membrane by spent plasmodium falciparum culture supernatant. Jordan Journal of Biological Sciences. 2013. Vol. 6, no. 1, pp.25-29.
https://search.emarefa.net/detail/BIM-326514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 29
Record ID
BIM-326514