Prevalence and risk factors for diabetes mellitus after renal transplantation

Abstract EN

Background : This study reviewed the prevalence of post Renal Transplantation Diabetes Mellitus (PRTDM) and risk factors for its occurance among renal transplant recipients. Methods : Records of all kidney recipients with no known diabetes mellitus prior to transplantation and patients with post-transplant period of more than 2 months were included.

The following parameters were studied as possible risk factors : age, sex, hypertension, family history of diabetes, immunosuppressive medications , body mass index and donors whether relative or not . Results : The 97 patients who studied, 20.62% had PRTDM(table I).

Family history of diabetes and older age of recipients did not differ significantly between recipients with versus without PRTDM.however, recipients who developed PRTDM had significantly higher body mass index (28.49 versus 25.21) with statistically significant difference (P < 0.05). Hypertension was prevalent more in recipients with PRTDM (65 % versus 53.24 %) this difference was statistically significant (P < 0.05).patients with unrelated donors showed higher incidance of PRTDM with significant result . Conclusion : Diabetes after renal transplantation occurs in significant number of patients.

Transplantation from related donors may be associated with lower risk of PRTDM.

Diabetes occure more in recipients with hypertensive and higher body mass index.