Effect of chicorium intybus extract on histological changes in liver and kidney of hypercholesterolemic rabbits

Abstract EN

In this study, the experiment was designed to investigate the effect of daily oral administration of (0.5gm / kg.

B.W) of chicory (Chicorium intybus) for one month on weight and histology of kidney and liver of hypercholesterolemic rabbits (induced by oral administration of 0.5 gm / kg of cholesterol dissolved in 3ml Soya bean oil) and compared this effect with medicial therapy used for atherosclerosis treatment .

The results revealed a significant increase (P < 0.05) the weights of livers and kidneys in hypercholesterolemic group when compared with other groups ,while the histopathological results showed histological changes in the livers and kidneys of hypercholesterolemic rabbits and also in chicory treated group when compared with other groups.