The effect of deep inspiration and forced expirattion on dopplertransmitral flow, cardiac output

Abstract EN

This study was carried out on 20 normal apparently healthy male volunteers, aged 18-36 years in order to study the effect of deep inspiration and forced expiration on mitral valve inflow, cardiac output, by using non-invasive techniques.

Mercury sphygmomanometer for measuring the blood pressure (BP), Doppler echocardiography for estimating of stroke volume (SV), cardiac output (CO), velocity time integral (VTI), Mitral valve area (MVA), pressure half time (PHT), acceleration, deceleration time of passive atrial filling E wave, acceleration time(T1), deceleration time (T2) and acceleration time (T3),deceleration time (T4) of atrial contraction, A wave.

The results : SV, CO, VTI were significantly higher and PHT significantly lower in baseline expiratory than inspiration.

There were no significant changes in MBP, HR, T1, T2, T3 and T4.

Comparison between deep inspiration and forced expiration shows that the MBP, SV, CO, VTI, PHT and T1were significantly higher during forced expiration than that of deep inspiration, where as there are no significant differences in HR, T2, T3 and T4.

Comparison between baseline quite breathing (inspiratory phase) and deep inspiration : The results indicate that there were no significant changes in SV,CO, MBP, HR, VTI, PHT, T1, T2, T3 and T4 between baseline and deep inspiration.

Comparison between control and forced expiration, shows no significant changes in SV, CO, HR, MBP, VTI, PHT, T1, T2, T3, and T4.

The aim of the present research is first: to investigate the changes of mitral valve inflow and its effect on cardiac output during deep inspiration and forced expiration.