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ABO-Incompatible kidney transplantation
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 3 (30 Jun. 2013), pp.463-472, 10 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-06-30
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Topics
Abstract EN
HLA sensitization and ABO incompatibility continue to pose a significant barrier to expansion of living donation.
In fact, either anti-blood or anti-donor HLA antibodies result in the occurrence of hyperacute rejection and graft loss.
Reducing this early rejection risk by planned desensitization protocols has clearly improved the outcome of ABO-incompatible (ABOi) kidney transplantation.
B-cell depletive therapy has replaced splenectomy, overcoming the disadvantages of the latter.
Plasma exchange techniques have considerably reduced antibody titers, allowing better results.
Thus, newer immunosuppressive protocols reduced early graft loss and early rejections episodes and, consequently, improved the long-term graft survival.
Therefore, ABOi kidney transplantation can be more broadly practiced, especially to expand the pool donor and to reduce the waiting time for transplantation.
American Psychological Association (APA)
Ayyash, Sumayyah. 2013. ABO-Incompatible kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 3, pp.463-472.
https://search.emarefa.net/detail/BIM-328433
Modern Language Association (MLA)
Ayyash, Sumayyah. ABO-Incompatible kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 3 (Jun. 2013), pp.463-472.
https://search.emarefa.net/detail/BIM-328433
American Medical Association (AMA)
Ayyash, Sumayyah. ABO-Incompatible kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 3, pp.463-472.
https://search.emarefa.net/detail/BIM-328433
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 469-472
Record ID
BIM-328433