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Impact of donor age on outcome of kidney transplantation from controlled donation after cardiac death
Joint Authors
Akoh, Yaqub A.
Tahawar, Rana A.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 4 (31 Dec. 2013), pp.673-681, 9 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-12-31
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Topics
- Heart
- Kidneys
- Diseases
- Cardiac arrests
- Heart failure
- Organ transplantation
- Complications(Medicine)
- Benefactors
Abstract EN
Previous reports regarding donation after cardiac death (DCD) have called for caution in extending the age of kidney donors beyond 60 years due to the risk of poor graft function.
The aim of this study was to determine the impact of donor age on renal transplantation from DCD in one center.
All DCD transplants from 2005 to 2009 were included in the study.
Immunosuppression and recipient follow-up were as per unit protocol.
Donor and recipient details were entered prospectively into a renal database and analyzed for graft outcome.
Of the 147 renal transplants, 102 were from donors <60 years old and 45 were from donors ≥ 60 years old.
The incidence of delayed graft function varied significantly according to donor-recipient age groups (P = 0.01).
The mean glomerular filtration rate at 12 months was 50.3 mL / min for transplants from young donors compared with 39.3 mL / min for transplants from old donors (P = 0.001).
The cumulative graft survival rates at 1 and 5 years were 88 % and 79 % for young donors, while for old donors these were 78 % and 72 %, respectively (P = 0.101).
By transplanting kidneys from old DCD donors into elderly patients, their survival is improved compared with dialysis, and organs from younger donors are made available for younger recipients.
American Psychological Association (APA)
Akoh, Yaqub A.& Tahawar, Rana A.. 2013. Impact of donor age on outcome of kidney transplantation from controlled donation after cardiac death. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 4, pp.673-681.
https://search.emarefa.net/detail/BIM-328437
Modern Language Association (MLA)
Akoh, Yaqub A.& Tahawar, Rana A.. Impact of donor age on outcome of kidney transplantation from controlled donation after cardiac death. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 4 (2013), pp.673-681.
https://search.emarefa.net/detail/BIM-328437
American Medical Association (AMA)
Akoh, Yaqub A.& Tahawar, Rana A.. Impact of donor age on outcome of kidney transplantation from controlled donation after cardiac death. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 4, pp.673-681.
https://search.emarefa.net/detail/BIM-328437
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 680-681
Record ID
BIM-328437