Outcome of individualized dialysate sodium concentration for hemodialysis patients
Joint Authors
Shawqi, Sahar
al-Shahawi, Yasir
Sani, Dawlat
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 3 (30 Jun. 2013), pp.507-513, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-06-30
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
To evaluate the individualization of dialysate sodium (Na +) concentration in hemodialysis (HD), we studied 40 stable chronic HD patients in a single-blind crossover design.
They underwent 36 consecutive HD sessions with the dialysate Na + concentration set at 138 mmol / L, followed by 36 sessions of dialysate Na + set to match the patients average pre-HD plasma Na + levels.
We multiplied the midweek pre-HD measured Na + by the Donnan coefficient of 0.95 (individualized Na +).
Pre-HD Na + dialysis sodium levels were nearly constant, with no variation between the two phases and a mean of 137.45 ± 2.04 mmol / L.
Post-HD serum Na + was significantly higher during the standard phase (139.7 ± 2 mmol / L) than during the individualized phase (137.1 ± 1.6 mmol / L).
Also, interdialytic weight gain (IDWG) was significantly more reduced during the individualized phase (3.25 ± 0.56 %) than during the standard phase (3.94 ± 0.92 %), P < 0.001.
Episodes of distressing symptoms including headache, muscle cramps and hypotension were significantly less frequent in the individualized phase.
The mean of the pre-HD and post-HD systolic and diastolic blood pressures significantly decreased during the individualized phase, and we could reduce the doses of antihypertensive drugs in 10 (33.33 %) patients.
Individualized dialysate Na + concentration was associated with a decrease in IDWG and dialysis hypotension and related symptoms and better BP control in stable chronic HD patients.
American Psychological Association (APA)
al-Shahawi, Yasir& Sani, Dawlat& Shawqi, Sahar. 2013. Outcome of individualized dialysate sodium concentration for hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 3, pp.507-513.
https://search.emarefa.net/detail/BIM-328491
Modern Language Association (MLA)
al-Shahawi, Yasir…[et al.]. Outcome of individualized dialysate sodium concentration for hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 3 (Jun. 2013), pp.507-513.
https://search.emarefa.net/detail/BIM-328491
American Medical Association (AMA)
al-Shahawi, Yasir& Sani, Dawlat& Shawqi, Sahar. Outcome of individualized dialysate sodium concentration for hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 3, pp.507-513.
https://search.emarefa.net/detail/BIM-328491
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 512-513
Record ID
BIM-328491