The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients : a single blind control trial

Abstract EN

Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity.

The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population.

The present study has been designed to evaluate the vitamin B 12 level in HP-infected CKD patients.

We assessed the serum levels of vitamin B 12 in 50 CKD patients with positive HP serology, one and three months after the eradication of HP infection.

There were significant differences between the serum levels of vitamin B 12 in the study patients before (806.98 ± 466.82) and after (760.36 ± 433.93) eradication treatment (P < 0.001).

We conclude that our study suggests the correlation between vitamin B 12 deficiency in CKD patients and the HP infection status.