Rhino-orbitocerebral mucormycosis in a patient with idiopathic crescentic glomerulonephritis
Joint Authors
Sanavi, Suzan
Afshin Majd, Siamak
Afshar, Rida
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 4 (31 Dec. 2013), pp.768-772, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-12-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Mucormycosis, caused by mucorales, is an acute, rapidly progressive infection associated with high mortality.
Rhino-orbitocerebral infection is the most common variant and is generally seen in association with immune deficiency syndromes.
Prompt medical treatment of this infection and debridement decreases the mortality rate.
We describe a 47-year-old man with crescentic glomerulonephritis on maintenance prednisolone therapy.
He had earlier received steroid and cyclophosphamide pulse therapies.
Renal functions improved following immunosuppressive treatment.
In the third month of maintenance therapy, he presented to us with left-sided facial swelling and bloody nasal discharge.
He had high blood sugar and acidic blood pH (ketoacidosis), probably due to steroid therapy.
Magnetic resonance imaging of the head and sinuses showed inflammation and mass in the ethmoid sinus and nose with partial septal destruction, proptosis, global destruction of the left eye, brain infarction and carotid artery obliteration.
Endoscopic biopsy of the sinuses revealed severe tissue necrosis.
Samples of nasal discharge and biopsy tissue showed aseptate hyphae on light microscopy and culture, compatible with Rhizopus.
The patient was treated with amphotericin B and multiple wound debridements along with ethmoidectomy and enucleation of the left eye.
He was discharged in good general condition but with mild right hemiparesis.
On follow-up examination at one year, there were no signs of fungal infection or renal dysfunction.
American Psychological Association (APA)
Sanavi, Suzan& Afshar, Rida& Afshin Majd, Siamak. 2013. Rhino-orbitocerebral mucormycosis in a patient with idiopathic crescentic glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 4, pp.768-772.
https://search.emarefa.net/detail/BIM-328691
Modern Language Association (MLA)
Sanavi, Suzan…[et al.]. Rhino-orbitocerebral mucormycosis in a patient with idiopathic crescentic glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 4 (2013), pp.768-772.
https://search.emarefa.net/detail/BIM-328691
American Medical Association (AMA)
Sanavi, Suzan& Afshar, Rida& Afshin Majd, Siamak. Rhino-orbitocerebral mucormycosis in a patient with idiopathic crescentic glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 4, pp.768-772.
https://search.emarefa.net/detail/BIM-328691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 771-772
Record ID
BIM-328691