Autosomal dominant polycystic kidney disease : new insights into treatment
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 2 (30 Apr. 2013), pp.230-234, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Autosomal dominant polycystic kidney disease (ADPKD) is the world's most common inherited kidney disease.
An increasing number of animal and human studies have enhanced our understanding of the molecular and cellular pathology of ADPKD.
New treatment options are being tested in clinical trials in spite of the failure of mammalian target of rapamycin inhibitor therapy.
The main and most effective therapy remains control of hypertension by renin-angiotensin-aldosterone system (RAAS) blockade.
This review focuses only on promising therapies, including dual inhibition of RAAS, vasopressin receptor antagonists, increased fluid intake, and blockade of certain receptors of cyclic adenosine monophosphate.
Also, the paper reviews what these advances mean to patients and clinicians and elaborates on how these changes can be immediately applied to clinical practice.
There is an urgent need for discovery of new therapies targeted toward ADPKD in comparison with therapeutic progress of all other renal diseases.
American Psychological Association (APA)
Hilal, Imad. 2013. Autosomal dominant polycystic kidney disease : new insights into treatment. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 2, pp.230-234.
https://search.emarefa.net/detail/BIM-328866
Modern Language Association (MLA)
Hilal, Imad. Autosomal dominant polycystic kidney disease : new insights into treatment. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 2 (2013), pp.230-234.
https://search.emarefa.net/detail/BIM-328866
American Medical Association (AMA)
Hilal, Imad. Autosomal dominant polycystic kidney disease : new insights into treatment. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 2, pp.230-234.
https://search.emarefa.net/detail/BIM-328866
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 233-234
Record ID
BIM-328866