HER2 Ile655Val single nucleotide polymorphism in patients with ovarian cancer
Joint Authors
Dehaghani, Alamtaj Samsami
Mujtahidi, Zahrah
Irfani, Nasr Allah
Malik Zadah, Mihyar
Haqq Shinas, Muhammad Rida
Qadiri, Abbas
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 15, Issue 1 (31 Jan. 2013), pp.1-3, 3 p.
Publisher
Publication Date
2013-01-31
Country of Publication
United Arab Emirates
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background : the association between HER2 Ile655Val single nucleotide polymorphism and cancer is controversial.
Objectives : the aim of our study was to investigate this polymorphism in patients with ovarian cancer.
Patients and Methods: Genomic DNA was extracted from peripheral blood leukocytes of 107 patients and 130 healthy women.
HER2 gene polymorphism was assessed by PCR-RFLP.
Results : no significant difference was observed in genotype and allele frequency between patient and control groups according to HER2 Ile655Val polymorphism.
The disease stage, age, and histological type were also not associated with the polymorphism.
Conclusions : our data showed that HER2 Ile655Val single nucleotide polymorphism was not significantly associated with onset, histological type, age, and stage of ovarian cancer in Iranian patients.
American Psychological Association (APA)
Mujtahidi, Zahrah& Irfani, Nasr Allah& Malik Zadah, Mihyar& Haqq Shinas, Muhammad Rida& Qadiri, Abbas& Dehaghani, Alamtaj Samsami. 2013. HER2 Ile655Val single nucleotide polymorphism in patients with ovarian cancer. Iranian Red Crescent Medical Journal،Vol. 15, no. 1, pp.1-3.
https://search.emarefa.net/detail/BIM-329030
Modern Language Association (MLA)
Mujtahidi, Zahrah…[et al.]. HER2 Ile655Val single nucleotide polymorphism in patients with ovarian cancer. Iranian Red Crescent Medical Journal Vol. 15, no. 1 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-329030
American Medical Association (AMA)
Mujtahidi, Zahrah& Irfani, Nasr Allah& Malik Zadah, Mihyar& Haqq Shinas, Muhammad Rida& Qadiri, Abbas& Dehaghani, Alamtaj Samsami. HER2 Ile655Val single nucleotide polymorphism in patients with ovarian cancer. Iranian Red Crescent Medical Journal. 2013. Vol. 15, no. 1, pp.1-3.
https://search.emarefa.net/detail/BIM-329030
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 3
Record ID
BIM-329030