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Crescentic glomerulonephritis developing in the course of idiopathic membranoproliferative glomerulonephritis
Joint Authors
Lal, Charanjit
Agarwal, Sanjay K.
Dinda, Amit K.
Gupta, Ruchika
Sharma, Aluk
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 2 (30 Apr. 2013), pp.333-337, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Membranoproliferative glomerulonephritis (MPGN) is a rare cause of the nephrotic syndrome in adults and children.
Though small focal crescents may be seen in up to 10 % of cases of MPGN, the presence of more than 50 % crescents (crescentic MPGN) is rare.
Very few cases of crescentic transformation of MPGN, documented by subsequent renal biopsies, have been described in the literature.
A young female patient underwent kidney biopsy for the nephrotic-nephritic syndrome and was diagnosed as idiopathic MPGN.
She was administered immunosuppressive therapy (steroids and cyclophosphamide), with which her renal functions stabilized.
Six months later, she presented with features suggestive of rapidly progressive renal failure and underwent a second renal biopsy.
The second biopsy showed crescentic glomerulonephritis with immune complex deposition, suggestive of MPGN.
A final diagnosis of crescentic transformation of MPGN was made.
Crescentic transformation of MPGN is a rare occurrence, but needs to be considered in a patient diagnosed as MPGN and presenting with rapidly progressive renal failure.
The cause of such transformation remains to be elucidated.
American Psychological Association (APA)
Sharma, Aluk& Gupta, Ruchika& Lal, Charanjit& Agarwal, Sanjay K.& Dinda, Amit K.. 2013. Crescentic glomerulonephritis developing in the course of idiopathic membranoproliferative glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 2, pp.333-337.
https://search.emarefa.net/detail/BIM-329036
Modern Language Association (MLA)
Sharma, Aluk…[et al.]. Crescentic glomerulonephritis developing in the course of idiopathic membranoproliferative glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 2 (2013), pp.333-337.
https://search.emarefa.net/detail/BIM-329036
American Medical Association (AMA)
Sharma, Aluk& Gupta, Ruchika& Lal, Charanjit& Agarwal, Sanjay K.& Dinda, Amit K.. Crescentic glomerulonephritis developing in the course of idiopathic membranoproliferative glomerulonephritis. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 2, pp.333-337.
https://search.emarefa.net/detail/BIM-329036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 337
Record ID
BIM-329036