Rapid accelerated hemodialysis in children with end-stage renal disease : a randomized clinical trial
Joint Authors
al-Hatw, Muhammad Khalid
Fadil, Fatinah
al-Barudi, Ramzi
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 1 (28 Feb. 2013), pp.22-29, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-02-28
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
In rapid accelerated hemodialysis (R-AHD), blood partially recirculates from the venous (outflow) to the arterial (inflow) line through a recirculation line (R) to selectively increase the filter blood flow rate (BFR).
R-AHDPR uses two blood pump segments at the patient segment of the arterial line and at (R).
To determine the effectiveness of R-AHD with regard to increasing anticoagulation and dialysis efficiency, we studied ten children with end-stage renal disease in two stages : stage 1 with 10 routine heparin R-AHD, then 10 half-dose heparin R-AHD, then 145 routine heparin R-AHD sessions for 1 month and then routine heparin double needle hemodialysis (DNHD) for one month (control).
In stage 2, we dialyzed the patients with 10 routine heparin-mixed AHDPR and DNHD sessions, then eight low-dose heparin R-AHDPR ” sessions, then one of the children with 10 no-heparin R-AHDPR sessions and then 10 routine heparin DNHD sessions ” (control).
Signs of blood clotting and dialysis efficiency were monitored.
Blood clots appeared in four out of 165 R-AHD0 (one pump circuit) sessions but in none of the 28 R-AHDPR sessions.
In stage 1, the mean urea reduction rate was 0.60, 0.60 and 0.70 for the R-AHD protocols, compared with 0.71 for the control (P > 0.05).
In stage 2, the arterial blood urea nitrogen was reduced by 0.66 ± 0.15 after an R-AHDPR period, compared with 0.79 ± 0.18 after a DNHD period (P = 0.059).
In conclusion, R-AHDPR allowed successful low heparin and no heparin hemodialysis in children without increasing the patients’ BFR.
However, the technique did not increase the efficiency of dialysis.
American Psychological Association (APA)
al-Hatw, Muhammad Khalid& Fadil, Fatinah& al-Barudi, Ramzi. 2013. Rapid accelerated hemodialysis in children with end-stage renal disease : a randomized clinical trial. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 1, pp.22-29.
https://search.emarefa.net/detail/BIM-329691
Modern Language Association (MLA)
al-Hatw, Muhammad Khalid…[et al.]. Rapid accelerated hemodialysis in children with end-stage renal disease : a randomized clinical trial. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 1 (2013), pp.22-29.
https://search.emarefa.net/detail/BIM-329691
American Medical Association (AMA)
al-Hatw, Muhammad Khalid& Fadil, Fatinah& al-Barudi, Ramzi. Rapid accelerated hemodialysis in children with end-stage renal disease : a randomized clinical trial. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 1, pp.22-29.
https://search.emarefa.net/detail/BIM-329691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 28-29
Record ID
BIM-329691