Ultrasound predictors of compensated liver cirrhosis in hemodialysis patients with hepatitis C
Joint Authors
Vidimliski, P. Dzikuva
Dzikova, S.
Salim, Gj.
Giliv, S.
Trajciska, L.
Pushivski, V.
Sikuli, A.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 1 (28 Feb. 2013), pp.30-35, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-02-28
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
- Liver
- Patients
- Psychological aspects
- Diseases
- Cirrhosis hepatis
- Hemodialysis
- Ultrasonic imaging
- Diagnosis
- Portal hypertension
- Hepatitis C
Abstract EN
Ultrasound examination was performed in 80 hemodialysis (HD) patients with chronic hepatitis C in order to determine the ultrasound predictors of compensated liver cirrhosis.
The ultrasound score (US) was calculated from the morphological parameters (liver size, morphology, surface, echogenicity and spleen volume) and the hemodynamic parameters (portal vein diameter and portal vein mean flow velocity).
The US ranged from 0 to 200, with a cut-off value of 66, for discrimination between absence and presence of liver cirrhosis.
A logistic regression model with stepwise variable selection was used to determine predictors of the progression of liver disease.
According to the calculated US, patients were divided into two groups.
The first group consisted of 37 (46.3 %) patients with US greater than 66, indicating the presence of compensated liver cirrhosis.
The second group included 43 (53.7 %) patients without liver cirrhosis, with US equal to or less than 66.
The value of liver morphology was significantly higher, but the portal vein flow velocity was significantly lower in patients with compensated liver cirrhosis compared with those without cirrhosis.
Furthermore, rounded liver surfaces and increased liver echogenicity were significantly more frequent in patients with compensated liver cirrhosis compared with the non-compensated group.
Logistic regression model with stepwise discriminant analysis identified liver morphology, liver echogenicity and portal vein mean flow velocity as independent ultrasound predictors of compensated liver cirrhosis in HD patients with chronic hepatitis C.
Ultrasound examination could be used for non-invasive diagnosis of compensated liver cirrhosis, with accurate estimation of the disease severity in HD patients with chronic hepatitis C.
American Psychological Association (APA)
Vidimliski, P. Dzikuva& Dzikova, S.& Salim, Gj.& Giliv, S.& Trajciska, L.& Pushivski, V.…[et al.]. 2013. Ultrasound predictors of compensated liver cirrhosis in hemodialysis patients with hepatitis C. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 1, pp.30-35.
https://search.emarefa.net/detail/BIM-329692
Modern Language Association (MLA)
Vidimliski, P. Dzikuva…[et al.]. Ultrasound predictors of compensated liver cirrhosis in hemodialysis patients with hepatitis C. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 1 (2013), pp.30-35.
https://search.emarefa.net/detail/BIM-329692
American Medical Association (AMA)
Vidimliski, P. Dzikuva& Dzikova, S.& Salim, Gj.& Giliv, S.& Trajciska, L.& Pushivski, V.…[et al.]. Ultrasound predictors of compensated liver cirrhosis in hemodialysis patients with hepatitis C. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 1, pp.30-35.
https://search.emarefa.net/detail/BIM-329692
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 34-35
Record ID
BIM-329692