Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis
Joint Authors
Tajbakhsh, Ramin
Qurbani, Mustafa
Dihghan, Muhammad
Azarhush, Ramin
Haghighi, Ali Nubakht
Sadani, Summayyah
Zadah, Suhaylah Samad
Kabutari, Maryam
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 1 (28 Feb. 2013), pp.36-40, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Mucocutaneous manifestations are common among patients on hemodialysis (HD).
This study was undertaken to determine the prevalence of mucocutaneous manifestations in patients with end-stage renal disease (ESRD) who are on HD.
In this cross-sectional, descriptive and analytic study conducted in 2009, 100 patients on HD at the Five Azar Hospital in Gorgan city were randomly selected.
All the patients underwent detailed examination by a dermatologist to look for lesions in the skin, hair, nail and mucous membranes; if felt necessary, biopsy was obtained from the lesions.
The findings were statistically analyzed using SPSS-13 software.
For evaluation of normality of distribution, Kolmogorov-Smirnov was used, for quantitative variables Mann–Whitney and T-test (abnormal distribution) were used and for qualitative variables, Chi-2 and Fisher were used.
In this study, Pvalue less than 0.05 was considered significant.
Fifty-one males and 49 females were enrolled.
The mean age was 49 ± 12 years.
Diabetes was the most common cause of ESRD.
In 95 % of the patients, at least one mucocutaneous manifestation was present.
Xerosis (78.3 %) was the most common lesion, followed by pruritus (39.1 %), lentigo (34.8 %), skin discoloration (32.6 %), leukonychia (32 %) and thinning of the nail bed (24 %).
Xerosis, scaling, lentigo, folliculitis, idiopathic guttate hypo-pigmentation, leukonychia and half and half nail were associated with age.
A significant relationship was seen between duration on dialysis and skin discoloration and leukonychia.
Clubbing had a significant association with calcium–phosphorus product (Ca × P).
There was a significant association between serum ferritin level and pruritus and tinea versicolor lesions.
Our study shows that mucocutaneous manifestations are common among patients with ESRD.
Identification of these manifestations and their association with causative factors are useful for preventing the lesions.
American Psychological Association (APA)
Tajbakhsh, Ramin& Dihghan, Muhammad& Azarhush, Ramin& Haghighi, Ali Nubakht& Sadani, Summayyah& Zadah, Suhaylah Samad…[et al.]. 2013. Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 1, pp.36-40.
https://search.emarefa.net/detail/BIM-329693
Modern Language Association (MLA)
Tajbakhsh, Ramin…[et al.]. Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 1 (2013), pp.36-40.
https://search.emarefa.net/detail/BIM-329693
American Medical Association (AMA)
Tajbakhsh, Ramin& Dihghan, Muhammad& Azarhush, Ramin& Haghighi, Ali Nubakht& Sadani, Summayyah& Zadah, Suhaylah Samad…[et al.]. Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 1, pp.36-40.
https://search.emarefa.net/detail/BIM-329693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 40
Record ID
BIM-329693