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The role of sex hormones, waist circumference, BMI and leptinemia in patients with acute renal failure
Joint Authors
al-Yasin, Hadif Zafir
Jalal, Maysa
Hani, Hind
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 50, Issue 2 (30 Jun. 2008), pp.1-18, 18 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2008-06-30
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Topics
Abstract EN
Background : Acute renal failure is characterized by impaired excretory endocrine homeostatic and metabolic functions of the kidneys.
Objective : The aim of this study is to look for the role of sex hormones, waist circumference and leptinemia in patients with acute renal failure.
Subjects and Methods : 55 subjects were involved in this study, 30 had acute renal failure and the remaining 25 subjects were normal healthy individuals who served as a control.
The age range of the patients was between 25 and 45 years with a mean of 37 ± 8.2 years.
Five mls of blood were withdrawn from each subject by vein puncture.
Enzyme linked immuno assay (ELISA) was used for the measurement of serum leptin level.
Radio immuno assay (RIA) technique was used for the measurements of testosterone Data were expressed as mean ± SD.
Results were evaluated using the student t-test for paired data.
Conventional methods were used for the correlation and regression analyses.
Results : Patients with acute renal failure show a significant increase in leptin level, BMI and waist circumference than healthy group.
On the other hand, testosterone level shows significant decrease while estradiol serum level shows a significant increase when compared with the healthy group in both genders although more significant in females.
Females with acute renal failure have significantly higher level of leptin than in males with acute renal failure as well as the anthropometrical measurements (BMI & waist circumference).
Conclusion : Increased level of serum leptin and estradiol in acute renal failure is a reflection of increased waist circumference of the patients and the effected renal parenchyma which make the ability of the kidney for biodegradation very poor.
On the other hand testesteron has a significant effect on serum leptin levels as can be seen through its positive effect in males rather in females.
American Psychological Association (APA)
al-Yasin, Hadif Zafir& Hani, Hind& Jalal, Maysa. 2008. The role of sex hormones, waist circumference, BMI and leptinemia in patients with acute renal failure. Journal of the Faculty of Medicine Baghdad،Vol. 50, no. 2, pp.1-18.
https://search.emarefa.net/detail/BIM-331251
Modern Language Association (MLA)
al-Yasin, Hadif Zafir…[et al.]. The role of sex hormones, waist circumference, BMI and leptinemia in patients with acute renal failure. Journal of the Faculty of Medicine Baghdad Vol. 50, no. 2 (2008), pp.1-18.
https://search.emarefa.net/detail/BIM-331251
American Medical Association (AMA)
al-Yasin, Hadif Zafir& Hani, Hind& Jalal, Maysa. The role of sex hormones, waist circumference, BMI and leptinemia in patients with acute renal failure. Journal of the Faculty of Medicine Baghdad. 2008. Vol. 50, no. 2, pp.1-18.
https://search.emarefa.net/detail/BIM-331251
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-331251