Correlation between some immunological parameters and clinical presentation in RA patients

Abstract EN

Background : Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity.

Aim : To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients.

Methods : Latex agglutination test (AG) & single radial immunoassay (SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA.

Results : IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients .

Conclusion : There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P < 0.01 with joint stiffness, joint swelling and Rheumatoid nodule, where as CRP was statistically significant P < 0.01withjoint swelling.