Effect of dichlorvos pesticide on fertility of laboratory male mice (Mus musculus L.)‎

Abstract EN

Dichlorvos is one of organophosphate insect pesticides which is widely distributed in environment.

This study deals with the effect of this pesticide on sperms number , sperm abnormalities and spermatogenesis in laboratory male mice (Mus musculus L.) which were treated with (0.1 mg / day , 0.05 mg/day ) of the pesticide for a period of 15 day.

intraperitoneal injection of Dichlorvos in laboratory mice resulted in a significant decrease in sperms number with both doses as compared with the control group.

The result also showed a significant increase of sperm abnormalities with both doses.

Moreover, pesticide injection caused a significant decrease in spermatogonia and primary spermatocyte with both doses whereas the statistical analysis did not show any significant difference in tubular diameter when compared with the control group.