Synthesis of some new 1, 3, 5-oxadiazine derivatives

Abstract EN

Some new derivatives of 1,3,5-oxadiazine-4-one (7-9) and 1,3,5-oxadiazine-4- thione (10-12) were synthesized using two different diamides (N, N′-Diaroyl urea / thiourea Compounds (1-6)).

N, N′-Diaroyl urea / thiourea compounds (1-6) were prepared by the reaction of urea and thiourea with benzoyl chloride and substituted benzoyl chloride respectively under basic conditions.

Cyclodehydration of the diamides under acidic conditions afforded the 1,3,5-oxadiazine compounds.

All compounds were identify by physical and spectroscopic methods.