Synthesis of some new heterocyclic compounds using phase transfer catalysis technique (PTC)‎

Abstract EN

A series of substituted chalcones (1-6) were synthesized and used to prepare some new five membered heterocyclic compounds (pyrazolines) (7-12) by their condensation with phenylhydrazine, and six membered heterocyclic compounds (pyrimidinones) (13-18) by their condensation with urea.

All reactions were carried out under phase transfer catalysis (PTC) technique, employing tributylbenzylammonium bromide (TBBAB) as a catalyst in 50 % aqueous sodium hydroxide in benzene (liquid-liquid system).

The structures of products were identified by physical and spectroscopic methods.