Psychiatric squele of sodium valproate versus carbamazepine in patients with primary generalized epilepsy
Joint Authors
al-Yasiri, Abd al-Rasul
Hasan, Zaki Nuh
Hasan, Hasan Aziz
Source
al-Kindy College Medical Journal
Issue
Vol. 4, Issue 2 (31 Dec. 2008), pp.77-82, 6 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2008-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : psychiatric and behavioral side effects are common in patients with epilepsy and it may represent an intrinsic feature of the disease itself or a side effect of the antiepileptic use.
Our aim in the present study is to assess the psychiatric side effects of Sodium Valproate and Carbamazepine .as these drugs are the most commonly used antiepileptic drugs in Iraq.
Methods : 80 patients with primary generalized epilepsy on Carbamazipine and 50 patients on Sodium Valproate were enrolled in the present study ; all the patients were assessed for any psychological disturbances using semi-structural interview based on the tenth edition of the international classification of the diseases (ICD 10) adopted by WHO Results : Thirty percent of patients taking Sodium Valproate and (9 %) of patients taking Carbamazipine were found to have depression while (16 %) of patients taking Sodium Valproate and (20 %) of patients taking Carbamazipine were found to have anxiety.
There were no reported psychosis, suicidal attempts, cognitive deficit and mania in both groups of patients in the present study.
Conclusion : carbamazipine is preferred to Sodium Valproate when the efficacy of both drugs is comparable.
American Psychological Association (APA)
Hasan, Zaki Nuh& al-Yasiri, Abd al-Rasul& Hasan, Hasan Aziz. 2008. Psychiatric squele of sodium valproate versus carbamazepine in patients with primary generalized epilepsy. al-Kindy College Medical Journal،Vol. 4, no. 2, pp.77-82.
https://search.emarefa.net/detail/BIM-331929
Modern Language Association (MLA)
Hasan, Zaki Nuh…[et al.]. Psychiatric squele of sodium valproate versus carbamazepine in patients with primary generalized epilepsy. al-Kindy College Medical Journal Vol. 4, no. 2 (2008), pp.77-82.
https://search.emarefa.net/detail/BIM-331929
American Medical Association (AMA)
Hasan, Zaki Nuh& al-Yasiri, Abd al-Rasul& Hasan, Hasan Aziz. Psychiatric squele of sodium valproate versus carbamazepine in patients with primary generalized epilepsy. al-Kindy College Medical Journal. 2008. Vol. 4, no. 2, pp.77-82.
https://search.emarefa.net/detail/BIM-331929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 82
Record ID
BIM-331929